Holders Manchester City were eliminated from the League Cup by West Ham United after a penalty shootout at London Stadium on Wednesday, ending Pep Guardiola's team's four-year domination of the competition.
ManchesterCity's hopes of regaining the Premier League title suffered a potentially grievous blow on Saturday as they were held to a goalless draw by struggling NorwichCity at Carrow Road.
Romelu Lukaku extended his impressive FA Cup scoring record by netting twice in Manchester United's 2-0 win at Huddersfield Town to earn Jose Mourinho's side a quarter-final tie at home to Brighton & Hove Albion.
News of all that's transpired on and off the football field
Images from Saturday's action in the Premier League.
Images from the Nations League matches played on Thursday.
Slovenia winger Valter Birsa said he expected England to fire on all cylinders after two poor performances when the two teams meet in their crunch Group C match in Port Elizabeth on Wednesday.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Juve forward Cristiano Ronaldo had an unusually quiet game after scoring a hat-trick against Atletico in last year's competition, although he came within inches of grabbing a last-gasp winner when he sent a shot just past the far post.
Manchester City went top of the Premier League after securing a controversial 2-0 win at Newcastle United on Sunday with an early Edin Dzeko goal and a stoppage time effort from Alvaro Negredo.
England's last appearance at this stage was in 1990 when they lost in a penalty shootout to West Germany in Turin while eight years later, in their first World Cup as an independent nation, Croatia lost to hosts and eventual winners France.
News of all that's transpired on and off the football field
Uruguay sealed their spot at the 2014 World Cup finals after a goalless draw at home to Jordan in the second leg of their intercontinental playoff on Wednesday saw them advance 5-0 on aggregate.
IMAGES from the English Premier League matches played on Sunday
The dazzling Lionel Messi returned from illness to score yet another double to help Barcelona ease into the knockout stages of the Champions League for a 13th successive year with their 2-0 win at Celtic on Wednesday.
Images from the FIFA World Cup qualifying matches on Sunday night.
Manchester United enjoyed a hugely satisfying Saturday, beating Everton 1-0 to go five points clear in the Premier League after challengers Arsenal and Aston Villa were held to home draws. Cristiano Ronaldo's 44th-minute penalty at Old Trafford was enough to give the champions 53 points from 23 matches.
Daley Blind's injury-time equaliser rescued a 1-1 draw for Manchester United against West Ham United on Sunday but a point was not enough to regain third spot in the Premier League.
Real Madrid brushed off the absence of Cristiano Ronaldo and Gareth Bale to beat Espanyol 2-0 away and maintain their 100 per cent start to the league season while matching the La Liga record of 16 consecutive victories.
But India clawed back into the game in the second quarter. While the team's defence held strong in the following minutes, the Indian attackers worked on creating scoring opportunities.
Millwall and Blackburn Rovers fought out a goalless stalemate in a scrappy FA Cup quarter-final on Sunday with both the Championship (second tier) sides going into the semi-final draw.
IMAGES from the English Premier League matches played on Saturday
Arsenal are going through a sticky patch, goals and points are drying up and injuries are mounting, so it is not the best time to entertain Manchester United on Saturday. Chelsea, who returned to the top last week on goal difference with a 5-0 thrashing of Sunderland, are at Blackburn Rovers on Sunday while Liverpool, stunned 2-1 at Tottenham Hotspur, are at home to West Bromwich Albion on Saturday.
Brazil and Argentina endured more frustration in the World Cup qualifiers with draws against Bolivia and Peru respectively.
A summary of Saturday's matches in the FA Cup.
Barcelona lost ground on La Liga leaders Real Madrid when their 11-match winning streak was snapped by Malaga, while Premier League pacesetters Chelsea dropped points at home to Burnley. Bayern Munich enjoyed a second-successive goalrush in the Bundesliga after routing Paderborn 6-0 while AS Roma lost ground to Serie A leaders Juventus after yet another draw. This and more from the happenings in the world of football over the weekend.
A round-up of Wednesday's action in the UEFA Champions League.
Chelsea missed the chance to reclaim top spot in the Premier League when they were held to a 1-1 home draw by West Ham United on Sunday, a day after Liverpool, Manchester United and Arsenal also drew.
Substitute Costa slipped the ball past the keeper from close range in the 48th minute of the second half to break the deadlock and extend Brazil's winning run to 11 matches.
News of all that's transpired on and off the football field
IMAGES from the Champions League matches played on Wednesday.
Images from the UEFA Champions League matches played on Wednesday.
On a good night for English clubs in the Europa League, Manchester United hammered AZ Alkmaar 4-0, while Wolverhampton Wanderers also thrashed Besiktas 4-0 in Group K, and Arsenal came from two goals down to draw 2-2 away to Standard Liege and finish first in their pool. The upset of the night came in Group J as Crivelli scored a 90th-minute winner against Borussia Moenchengladbach to send Basaksehir through and knock the Germans out, with AS Roma grabbing the runner-up spot thanks to a 2-2 home draw with Wolfsberger as the Europa League group stage concluded on Thursday.
Two big derbies and an eventful weekend of football awaits us all...
Celtic, who won Europe's premier club competition in 1967, set up a clash with Romanians Cluj in the next stage after a 2-0 win at Nomme Kalju completed a 7-0 aggregate rout of the Estonian champions.
Images from Sunday night's English Premier League matches.
